Ho bolela sehlooho se reng "Tranexamic acid e" ke lithethefatsi antifibrinolytic,-ba khahlanong le a hlabang le antiallergic bohato, hammoho le a phatlalatsa e le hantle hemostatic ha bleedings tse amanang le ho eketseha ha fibrinolysis. Ho ea mantlha ea lithethefatsi ke thibelo ea plasminogen activator le plasmin thibelo ya sebopeho sa peptides mafolofolo le kinins ameha ka ho toba ka liphetoho a hlabang le alejiki. Ho phaella moo, e le sesebelisoa se kang "acid e Tranexamic", haholo lengthens sa thrombin nako. Mabapi le litšobotsi pharmacokinetics ea lithethefatsi-ba khahlanong le fibrinolytic mor'a a e-ja e ananelang 30-50% ya dosing lona ka lekhetlo la pele, ka ho fetisisa ho lemohiloeng lero la mali concentrations lekholo - metsotso lekholo le mashome a robeli ka mor'a ho sebelisoa. Antifibrinolytic sebetsa ka lisele tse boloketsoeng lesometlhano - lihora tse leshome le metso e supileng, le lero la mali - bakeng sa lihora tse supileng kapa tse robeli ka mor'a tsamaiso ya lithethefatsi "acid e Tranexamic". Theko oa sesebelisoa sena ka 1300 li-ruble, 'me u ka e reka ka hoo e ka bang mong le e mong drugstore.
Antifibrinolytic lithethefatsi hlahisoang ka mokgwa wa matlapa a makholo a mabeli le mashome a mahlano kapa le makholo a mahlano milligram, e le tharollo bakeng sa ente, hammoho le le tharollo ne a rerile hore tsamaiso molomo. Kaofela ha diforomo ka holimo litekanyetso li behoa ke hantle loketseng bakeng sa kalafo le thibelo ea mali, halefile e leng keketseho ea fibrinolysis kakaretso. Ka mohlala, hangata ha ho tsamaisoa moemeli, o bitswang "acid e Tranexamic" ka lihlahala tse kotsi tsa tšoelesa ea senya kapa manyeme, kankere ea mali, ho buoa tsereletsi ka makala a sefuba, le mafu a sebete. Manual tlosoe placenta le postpartum hemorrhage ba boetse ba akarelletsa lethathamo la bonahala ho eang ka. Ho phaella moo, ho sebelisa lithethefatsi "acid e Tranexamic" li tlameha tsa haematuria, angioedema, alejiki dermatitis, eczema, chefo le lithethefatsi lekhopho, hives. Ho phaella moo, lithethefatsi ena e bontšoa ho pharyngitis mafolofolo, laryngitis, tonsillitis, stomatitis, nasal, uterine le mali mala, leino tse qotsitsoeng ka bakuli ba na le boloetse ba hemorrhagic diathesis. Hammoho ho sesebelisoa e kang "acid e Tranexamic", le khoeli le khoeli, tse ling tse ho feta tsa melupe.
Ha e le kopo e itseng le dosing meriana, ho e mong le e Haeba ba ba beha le batho ka bomong, e thehiloeng le boemo bo fanoeng litleleniki tsa. Leha ho le joalo, e le busa, ka nako ya e lumelloa ho nka ka ho na dikgerama fetang 1-1.5. Tabeng ena, ho sebelisa multiplicity ke makhetlo a mabeli ho a mane ka letsatsi, 'me ka nako ea phekolo - ho tloha matsatsi a mararo ho leshome le metso e mehlano. Single lethal dose bakeng sa tsamaiso intravenous ke 10-15 mg, / lik'hilograma.
The contraindications ka sehloohong la ho ea ho sebelisa sesebelisoa sena ke maemo a kang hemorrhage subarachnoid, thromboembolism, ho hloleha renal, phytoteratology mmala pono, 'me thrombosis tebileng mothapo. Ho phaella moo, o lokela ho sebelisa meriana ena tabeng ea hypersensitivity mong kapa ho ima. Le litla-morao tse amanang le ho noa la mahlahana a khahlanong le fibrinolytic, e bonahale e le molikoalikoane, ho ke boroko, hypotension, tachycardia, bofokoli, 'me bohloko sefubeng.