"Thiotriazoline": litaelo tsa tšebeliso

Na u ho saena lithethefatsi "Thiotriazoline"? tabeng ea ho sebelisa tataiso ena meriana tla hlalosa ka ho qaqileng sehloohong tse teng. Ho phaella moo, re tla u bolella mabapi le mokgwa oo lithethefatsi kena thekiso o ile a re, e leng o na le matšoao, litla-morao 'me contraindications.

Sebopeho sa ambalaji lithethefatsi le mofuta o sa lokolloe

Ka mofuta ofe ho lokolloa moriana o "Thiotriazoline"? Litaelo tsebisa hore ho na le a 'maloa a mefuta e sa tšoaneng. Ka ho fetisisa ratoa ke tsena:

• A tharollo ne a rerile hore intramuscular le intravenous ente. 1 di ml le moemeli na le 0,025 g, Thiotriazoline. E boetse e le moriana o le dikarolo boikhethelo ka mokgwa wa metsi bakeng sa ente. Lithethefatsi e fumaneha ka 4 di ml ampoules (kenngoa ka lebokose la).
• "Thiotriazoline" leihlo marotholi. Ka ho sebelisa jwalo tataiso bolela fana hore 5 di ml e na le 50 mg, ea lithethefatsi Thiotriazoline, hammoho le lintho tse ling. Lithethefatsi e rekiswa ka libotlolo tsa polasetiki, droppers, kenngoa ka lebokoseng lebokoso.
• "Thiotriazoline" lipilisi. Litaelo ho mofuta ona oa lithethefatsi e fana ka hore ho e 'ngoe e tšoeu matlapa chitja le e sephara holim'a metsi leng 100 mg, morfoliniymetiltriazoliltioatsetata, kapa seo ho thoeng ke Thiotriazoline. E le dikarolo tse eketsehileng tsa moriana o se sebetsa litapole starch, microcrystalline selulose, le tlaase limolek'hule boima povidone, k'halsiamo stearate le sucrose. E le busa, ka sephutheloana lebokoso na le matlapa a 50.

pharmacodynamics

ke pheko e le "Thiotriazoline" ke efe? Litaelo tsa Sebelisa e bolela hore lithethefatsi ena antioxidant. bokgoni lona phahameng ka lebaka la antioxidant, antiischemic, immunomodulatory le lera botsitso thepa.

O ne a nka meriana ho thibela ho timetsoa ha hepatocytes, tlatsetsa ho hlaphoheloa ba bona, ho fokotsa tekanyo ea mafura khukhuneloa, ho fellang ka aa tlwaelegileng oa protheine, k'habohaedreite, lipid le pigment phapanyetsano, le ho fokotsa monyetla oa ho ata ha necrosis tsentrolobulyarnyh e le 'mele tse kang sebete. Ho feta moo, motho ea mafolofolo lithethefatsi ntlafatsa ho itšehla thajana le ho tswakana ba bile, normalizes sebopeho lona (lik'hemik'hale).

The thepa ya moriana

Kamoo o na le makgetha a ho ya lithethefatsi "Thiotriazoline"? Litaelo bakeng sa ho sebelisoa ea lithethefatsi e hlokahalang bakeng sa ho bala. Ka mor'a hore tsohle, feela sona ka sebele u ka ithuta ka seo lithethefatsi nkoa lowers thibelo ea dithulaganyo oxidative ka ho Krebs potoloho, ea bolokang intracellular ATP letlole la, hammoho le kgothaletsa ho Tshebediso ya (compensatory) anaerobic glycolysis.

Hape ela hloko hore ka mor'a ho nka lithethefatsi le mafolo-folo ntho qala ho ebe o kenya tshebetsong tsamaiso antioxidant, mafura thibela metsoako dithulaganyo oxidative libakeng tse ischemic ea 'mele. Ho phaella moo, lithethefatsi ena ntlafatsa thepa le (rheology) mali ka lebaka la Tshebediso ya ea tsamaiso fibrinolytic.

The antioxidant thepa ea lithethefatsi o ile a bontša ka ho ha e le hantle hore sebōpeho sa molek'hule ba tiotrazolina ions sebabole, tšoauoa ka ho kena moea le phokotso likarolo, hammoho le e phahameng naetrojene, eo tlama e chelete ka tsela e feteletseng ea ions hydrogen.

Hape re lokela ho hlokomela hore motho ea mafolofolo motsoako lithethefatsi ka itšoara le radicals lipid le mefuta e arabelang oksijene. Sena ke ka lebaka la ho phatlalatsoe thepa phokotso ea sehlopha thiol. Ho phaella moo, moriana o thibela sebopeho sa mefuta e arabelang oksijene, joalo antiradical reactivating enzyme e catalase, glutathione peroxidase le superoxide dismutase.

Pharmacokinetics

Hore na meriana e ananelang "Thiotriazoline"? Taeo e bolela hore nako poluabsorbtsii lithethefatsi ke metsotso e 30 le bioavailability - 65,5%.

Palo e kahodimodimo ea mahloriso ea mali ho bolela e fihlellwa ka lihora tse 1.4 ka mor'a tsamaiso. Ho buisana le liprotheine ha feta 10%.

Lintho tse ngata tse khōlō, meriana bakoang ka lisele tsa sebete, pelo, mala, spleen le liphio, 'me tse nyenyane - ka intestine tse nyenyane le matšoafo. Thiotriazoline excreted haholo-holo ke liphio.

ya litatoli na

Haeba ho na le ba bopengwi ka abeloa lipilisi, liente le leihlo marotholi "Thiotriazoline"? tabeng ea ho sebelisa mefuta ena ea ho ruta e bontša matšoao tse latelang:

• ho thatafala ha sebete;
• chefo sebete senya, joala, bongata ba kokwanahloko, le lithethefatsi (mohlala, ka mor'a ho amohela lithibela-mafu, antiviral lithethefatsi,-ba khahlanong le lefuba le-ba khahlanong le hlahala mahlahana, lithibela-pelehi molomo le antidepressants tricyclic);
• foleng bongata ba kokwanahloko lefu la sebete;
• joala lefu la sebete sa foleng ka tsela e itekanetseng ho mosebetsi fokolang haholo;
• tse mafura sebete degeneration.

Bontšang bakeng sa tšebeliso marotholi:

• mafu corneal;
• chesa kapa leihlo likotsi;
• bongata ba kokwanahloko conjunctivitis.

Hobaneng ntse sebelisa mahlo lithethefatsi "Thiotriazoline"? Litaelo (marotholi a ka rekoa ka drugstore efe kapa efe) tsebisa hore meriana ena e atisa ho ba laela hore ho thibela leihlo omileng, eyestrain, le mafu a mang a hlabang le litho tse bonwang.

Matlapa litekanyetso li behoa

Ke lokela ho sebelisa "Thiotriazoline" Letlapa? Manual e na le tlhahisoleseding e le lithethefatsi lokela ho ho nkoa ka ka hare feela. E le busa, thiotriazolin thonya 1 kapa 2 matlapa ka makhetlo a mane ka letsatsi ka matsatsi a 25-30.

The nako ya kalafo le moemeli ena lokela ho ikemisetsa ka ho ngaka ka motheo oa motho (ho itšetlehile ka tsela e le ho tiea tsa lefu jaana).

The tharollo ea lithethefatsi "Thiotriazoline": litaelo tsa tšebeliso

Liente "Thiotriazoline" etsa intramuscularly kapa a entoe. litekanyetso li behoa bona e behilweng ke ngaka (ho itšetlehile ka le lefu lena). Myocardial infarction le lefu la sebete lithethefatsi butle tshelwa entoe ka 2 di ml makhetlo a 2-3 ka letsatsi. Ka ho thatafala ha sebete moriana o laolwa intramuscularly (2 di ml 2-3 linako tse ling ka letsatsi). Mokhoa oa ho kalafo ke matsatsi a 60.

Leihlo marotholi "Thiotriazoline": litaelo tsa tšebeliso

Leihlo marotholi "Thiotriazoline" kentseng ka karaoke tren conjunctival. Ka tloaelo, ka litekanyetso li behoa bakeng sa batho ba baholo ke 2 marotholi a makhetlo a 4 ka letsatsi. Mabapi le bana, ka tjhelete e ya moriana o ikemiselitse feela ke ngaka ea bana e. The nako ya kalafo le marotholi a mahlo le tlameha ho hlomamisa ka ho ngaka ho ba teng.

E le busa, ka nako ya kalafo le thulusi ena e ha ho na ho feta libeke tse 2. Empa ha ho na ntlafatso e hlokomela, thupelo le ka bontšoa ho fihlela ho ka khoeli.

Tabeng ea diso a pharaletseng a litho tsa ka hare tse bonwang le tebileng, ebe dropwise phaella tabeng ea ho liente ocular laolwa (litokisetso ngoe).

Bakeng sa ho thibela ho omisa ea lera la leihlo (a ntse a sebetsa ka k'homphieutha), o lokela ho sebelisa moriana 2 marotholi motšehare ka karohano ya dihora tse 2.

litla-morao

ke eng litla-morao tsa moriana ka etsa hore "Thiotriazoline" (Shots)? Litaelo ho mokhoa ona o bolela hore lithethefatsi e hantle mameletse ka ka tlhompho. Leha ho le joalo, ho sebelisa lithethefatsi ho nkoa ka ntse etsahala liphetoho undesired.

• Central tsamaiso ea methapo: molikoalikoane, ho fokola, ringing litsebeng le.
• Tshilong ya dijo pampitšana: molomo o omileng, ho nyekoa ke pelo, bloating.
• Lijana le pelo, e ile ea eketseha khatello ea mali, tachycardia, arrhythmia, bohloko ba pelo.
• Matšoafo tsamaiso e khopo: asma le bokhutšoanyane phefumoloho.
• Allergy: feberu, liphetoho hypersensitivity, angioedema.
• liphetoho Local: redness le tingling boikutlo sebakeng seo ente.
• liphetoho Dermatological: e phallang letlalo, ho hlohlona, hives.

Ha e le marotholi a mahlo, hore ka karolo ea bona litla-morao li ne li hlokomela.

ditshebeditsano lithethefatsi

Ho ea ka ka litsebi, lithethefatsi "Thiotriazoline" ka sebelisoa hammoho le meriana mantlha ne a rerile hore ho phekola lefu gogoga pelo. Sena ke ka ntlha ya go ha e le hantle hore re lithethefatsi ke moemeli cardioprotective.

Ho lokela ho hlokomeloe hore lithethefatsi e lumelloa ho sebelisoa ka nako le meriana eo ba abeloa ho ea kalafo loketseng lefu la sebete etiology.

Leihlo marotholi "Thiotriazoline" ka abeloa ho ea bakhachane le nakong diabolololo. E lokela ho ile a bolela hore sebopeho sa lihlahisoa o ile a re ba lumelloa ho sebelisa ka kopanelo le mekhoa e meng ea meriana.

Joala le Lithethefatsi "Tiatriazolin" matlafatsa ketso e mong le ba bang. Tabeng ena, ho sebelisa ha bona pataganeng e thibetsoe.

lemosa

Sebopeho se akarelletsa sucrose nkoa matlapa (ka chelete ea 2,8 mg, ka ho ya ka Letlapa). Kahoo, ho lethal dose lebetsoeng le letsatsi ya meriana ka ba le ka 22,4 mg, ea ntho ena. Ha e le hantle ena e lokela ho tseba hore na bakuli, bakuli ba le lefu la tsoekere mellitus.

Mekhoa le linako tsa polokelo

Feletseng mefuteng eohle ea "Tiatriazolin" lithethefatsi lokela ho ho sireletswa ho khanya le finyella bana ba ka mocheso oa likhato ho tloha 14 ho 26. The raka, athe bophelo ba lithethefatsi ke lilemo tse 3.