Phekolo ea kgatelelo ya madi bohlokwa

Pele ho kgethwa ha kalafo ka bakuli ba kgatelelo ya madi a khanna letsatsi go baya leitlho ea khatello ea mali. Sena ke hlokahala e le hore ho theha profil ea kgatelelo ya madi. Ka beha liphetoho diurnal ka khatello ea mali li khethoa phekolo e lekaneng ea meriana.

Phekolo ea kgatelelo ya madi e kenyeletsa mahlahana medicamentous le meriana. Bao e seng diokobatsi kalafo ea lefu lena ke haholo-holo ka ho boloka bophelo bo phetseng hantle. Le ea bohlokoa haholo ke aa tlwaelegileng oa ho robala bosiu, e thibelang tšebeliso ea letsoai, le cessation feletseng tsa ho tsuba le ho noa joala ka, boima ba 'mele le kamehla ho ikoetlisa.

Lithethefatsi kalafo ea kgatelelo ya madi kenyelletsa ditokiseletso taolo litokisetso meriana ea lihlopha tsena tse latelang:

- diuretics

- beta-blockers

- angiotensin-fetola inhibitors potlakisang tsebetso ea lik'hemik'hale

- khalsiamo le kanaleng blockers

Diuretics - Ba bang ba ka ho fetisisa ratoa lithethefatsi bakeng sa ho theola khatello ea mali. Khatello ea phokotso le hlaha ka lebaka la ho fokotseha ha ba modumo ea mokelikeli. Sa rateheng liphello tsa ho sebelisa ha bona ke ea fokotseha ka ho kopanela liphate, photosensitivity, liphello tsa pancreatitis, e ile ea eketseha k'holeseterole palo yohle, bofokoli mesifa, molikoalikoane, ho fokotseha takatso ea lijo, hypokalaemia. Bakeng sa o qenehela diuretics fapana tšoauoa ka tsoelo-pele ea hyperkalemia eo e ka etsa hore tsoelo-pele ea mafu endocrine, intrahepatic cholestasis, qhala tsa rheology mali.

khatello ea beta-blockers tlaase ea mali ka ho fokotsa khumo cardiac le thibelo ya renin tswakana. Ba kopanya hantle le diuretics le k'halsiamo khahlanong le lōna. Ea ho phekola ba beta-blockers ke ho hlokahala hore ka tsela e nepahetseng ho ikamahanya le lethal dose e balletsweng ya moriana. Overdose bontša tsoelo-pele ea bradycardia matla, hypotension, cardiac conduction. Ka bakuli ba pataganeng obstruction bronchial ka ntshetsa pele a tsoela pele ho bronchospasm. litokisetso tsena ha lia lokela ho tsamaisoa ho bakuli ba asma bronchial, insulin e itšetlehileng ka lefu la tsoekere mellitus, pheriferale vascular lefu. Kalafo ya bohlokwa kgatelelo ya madi beta-blockers qala ka tekanyetso e nyenyane, ho laola lebelo leo pelo le khatello ea mali, ka ho ba sieo ha le mathata eketsa lethal dose ya moriana.

Ace inhibitors - matla vasodilators, ke eo nako e telele ho laola ho thibela pressor phello ea ntlha e ka sehloohong - angiotensin. lithethefatsi tsena li ka thibela ho sithabela tsa bradykinin, thusa ho eketsa maemo mali a prostaglandins vasodilatory, thusa ka ha pelo. litla bohloko tsa lithethefatsi tsena li ka ba khohlela, angioedema, hyperkalemia, lekhopho, ho tsekela, takatso ea botona kapa u mofutsana 'me pherekano tatso. Ka sehloohong morero oa contraindication Ace inhibitors e omimvo renal mothapo constriction, kaha nyeoeng ena ho khatello ea mali ea eketseha ka lebaka la ho eketseha renin mali boo lithethefatsi tsena li ka ha ba na e le hantle.

blockers k'halsiamo le kanaleng fokotsa lebelo leo pelo, fokotsa khatello ea mali, empa ba bang ba na le litsobotsi tse mpe, jwalo ka hlooho e matla, e phallang ea sefahleho. Jwale, lithethefatsi tsena li ka go tlhaolega sebediswa bakeng sa kalafo ya maqakabetsi hypertension.

Phekolo ea kgatelelo ya madi e itšetlehile ka tekanyo e maloetse. Ho isa tekanyong 1 go tlhaolega sebediswa kalafo bao e seng diokobatsi. Hypertension lefu la pelo 2 likhato hloka ho khethoa ka tsela ea kalafo lithethefatsi bongaka. Ha lefu lena le ke likhato 3 meriana e lokela ho ba kamehla.

Thibela ntshetsopele ya lefu leha e le efe ha ho le thata hakaale, kamoo ho ka tšoara eona. Thibelo ea lefu hypertension ke tlosa mabaka a etiological ya lefu lena le, e latelang phelang ka eona e ka bophelo bo botle.