Metamizole

"Metamizole" le fana ka-ba khahlanong le a hlabang lona, antipyretic le phello analgesic e loketseng ha e le hantle hore thibela tswakana tsa prostaglandins tloha acid e arachidonic, ferekanngoa khanna bohloko litakatso eketsa mocheso phetiso le eketsa monyako oa bohloko nahanela.

O ile a re ea lithethefatsi e hantle ananelang tswa pampitšana gastrointestinal, moo hydrolyzed le a sebetsang a metabolite thehoa hoo e ka bang halofo ea betsang ba ho liprotheine mali. Khumo ea lithethefatsi moroto, e le ho kenella ka hare ho ka lebese.

"Metamizole" - litaelo tsa tšebeliso

moriana o ile a bontša bakeng sa phokotso ea bohloko se hlahang ho yona efe kapa efe, ebang neuralgia, ho tšoaroa ke hlooho, sciatica le myositis. O ile a boela a amohela ntaramane, fevers rheumatism le maloetse a mang.

E kgothaletswa ho nka "Metamizole" ho tloha mg, 250 ho tse 500 ka molomo, sena se lokela ho etsoa ka makhetlo a 2-3 ka letsatsi. The lethal dose ea letsatsi le letsatsi ba lokela ho sa feteng 3g, ka lethal dose ea se nang molekane ea lokela ho ba moholo ho feta 1 mob mobile.

Bana ba lilemo li lilemo tse 2-3 ba khothalletsoa ho nka ho fihlela ho 50-100 mg, ea moriana, a le lilemo li tse hlano -100-200mg, ho lilemo tse supileng -200 mg, le ho fihlela ho lilemo tse 14 -250-300mg itse ho bolela, ho e amohela ho latela dikgothaletso tseo.

Hape, "Metamizole sodium" ka nkoa entoe, intramuscularly, 'me, ka nako e tšoanang e laolwa ho fihlela ho ka makhetlo a mararo nakong ea letsatsi, empa dikgerama se fetang 2 ka letsatsi,' me bana e kgothaletswa ho nka 0.1-0.2 di ml ka ho ya ka 10 kilogerama mele.

Contraindications

E sa kgothaletswa ho noa meriana ena ka ho ba teng ha bronchospasm, phahameng nahanela ho Metamizole, mafu hematopoiesis, lefa haemolytic khaello ea mali, renal kapa e amanang le sebete insufficiency nakong ea bokhachane le ho diabolololo.

litla khoneha lehlakoreng

Fumana moriana o "Metamizole" ho ka etsa hore liketsahalo tse kang nephritis interstitial, oliguria, moroto le fetoha e khubelu, proteinuria, anuria. Hape, kulisa ka 'na etsahala ka conjunctivitis, urticaria, angioedema,' me makala ka linako tse ling anaphylactic ka etsahala, bronchospastic lefu, Lyell lefu. Leukopenia, fokotseha khatello ea mali, agranulocytosis, thrombocytopenia, infiltrates ka site ya tsamaiso e ka boela ho be ka lehlakoreng le phello e la moriana.

Hlokolosi ho nka "Metamizole sodium" ke ho hlokahala hore ho ho sithabela multiple, ho ba teng ha ea bohlokoa hypotension, myocardial infarction, bokhoba ba tahi le sa foleng le qalang makala.

Haeba u hloka nako e telele ea lithethefatsi ena, ho ke ke ho hlokahala hore ho ka hloko laola ho hlophisoa 'me boemo ba mali a pheriferale.

Moketeng oa lenyalo tsoa hong le chlorpromazine ka ntshetsa pele hyperthermia. "Metamizole 'e sa ho kopantswe le benzylpenicillin baemeli colloidal mali le lintho radiopaque.

Ka morero oa ho ea lithethefatsi sena ka lithibela-pelehi hormonal, analgesics bao e seng narcotic, allopurinol le antidepressants tricyclic a ka baka ntlafatsoa litla nang le chefo e.

Fumaneha hape le "Metamizol-sodium-Pitofenone Fenpiveriniya lethal gene" eo ke mokhoa kopantswe fana spasmolytic le analgesic sebediswa.

Ha overdose le hlaha ho nyekoa ke pelo, oliguria, cramps, gastralgia, mali phokotso khatello, hypothermia, dyspnea, tachycardia, tinnitus, lightheadedness, ho otsela, a hlobaetsang le agranulocytosis, shoele litho tsa mesifa matšoafo, phytoteratology kelo-hloko, lefu hemorrhagic.

Maemong a joalo, gastric lavage o etsoa sebedisa fatang amohetse letsoai laxatives le kamehla butswe k'habone. ka boela ho phethahatsoa hemodialysis, qobelloa diuresis, 'me ka ho ba teng ha cramps - ka / diazepam tsamaisoa le ka potlako ho nka bohato barbiturates.