Manaka "Diflucan" - le bolela "Fluconazole"

Manaka "Diflucan" - le bolela "Fluconazole" - ke moemeli antifungal le le phello e haholo e itseng. Lithethefatsi khonang ho thibela mosebetsi oa ba bang enzyme, thibela metsoako phetoho ya lanosterol ho ergosterol. Ho phaella moo, lithethefatsi eketsa e lumellang metsi ho kena ea lera la seleng, ho thibela boikatiso le kgolo ya likokoana-hloko. Lithethefatsi ke atlehang nkang monyetla fungal halefisoa ke li-fungus genus Candida, ho akarelletsa le generalized immunosuppression mefuta candidiasis mobung. Le meriana ea molomo o absorbability molemo. Ka tekanyo ea absorption e sa ameha ka ho ja lijo. The bioavailability ea lithethefatsi ke ka 90%. Palo e kahodimodimo dikahare maling fihla pheko ka mor'a metsotso e 30-90. Lithethefatsi e hantle ajoa lisele le maro a phunyeletse ka lebese. E lokela ho ile a bolela hore theko ea lithethefatsi "Fluconazole" taelo ea boholo tlaase ho feta boleng ba "Diflucan" (nakong e fetileng e tla lokela ho lefa ho tloha li-ruble tse makholo a mane tse makholo a robeli).

ya litatoli na

Medicine "Fluconazole" (manaka "Diflucan") abetsoe ka meningitis cryptococcal, cryptococcosis le localizations tse ling cryptococcal tshwaetso ka bakuli ba karabelo boitshireletso tloaelehileng le nang le mefuta e fapaneng ya immunosuppression. Ke bopaki ba candidiasis kenyeletsa generalized mofuta, disseminated candidiasis, candidemia, le mefuta e meng ea tšoaetso ea itaolang bakoa ke fungus e Candida. moriana buelloa bakeng sa thibelo ea mafu a tsoaetsanang fungal ka bakuli ba lihlahala tse kotsi tsa botho ba ka. Abeloa moemeli bakeng sa maoto a mycosis, groin, 'mele.

dosing Melao

Manaka "Diflucan" - le bolela "Fluconazole" - laetsoeng ho bakuli ba lilemo tse leshome le metso e mehlano ka boima e moholo ho lik'hilograma tse 50. Ha tšoaetso ea cryptococcal ya selegae le fapaneng ka letsatsi la pele ho lethal dose e le ba 400 mg,. Ka mor'a moo, ka tjhelete e ya moriana o fokotsoa hore mg, 200 ka letsatsi. Nako ea phekolo ka pathologies tsena itšetlehile ka ka bokgoni ba ho kalafo, e leng se tiisoa ke lithuto tsa mycological. Kopo ea meningitis cryptococcal lokela nka bonyane libeke tse tšeletseng ho ea ho ba robeli. Ha disseminated candidiasis, candidemia, le mefuta e meng ea Candida tšoaetso ea itaolang ka letsatsi la pele ka tjhelete e ya lithethefatsi - 400 mg,, litekanyetso li behoa ea e fokotsehile ho 200 mg,. Tabeng ea lekana katleho ea phekolo litekanyetso li behoa ea ea eketseha khutlela 400 mg,. Ka nako ea phekolo e itšetlehile ka ho atleha ha mokhoa oa.

setlamorao

Manaka "Diflucan" - lithethefatsi "Fluconazole" - ka etsa hore ho tsekela, bohloko ka hlooho, mpeng, bohloko mpeng, takatso ea botona kapa mafutsana, ho nyekoa ke pelo. Motheong oa kalafo ka ntshetsa pele thrombocytopenia, kulisa tse kang ho ruruha ea sefahleho, epidermal chefo necrolysis, letlalo ho hlohlona. matlapa Analogs ka etsa hore ho qhala ba sebete, a liphio, hypokalemia, hypertriglyceridemia.

Contraindications

U se ke ua laela la lithethefatsi pele ho ka ba lilemo li 4, tabeng ea ho se mamellane ea likarolo tsa eona. Contraindicated kopantswe sebelisoa le moriana o "Terfenadine", "Astemizole" le tse ling tse tlatsetsang lelefatsa QT-karohano. Temoso nakong phekolo le bontša predisposition ho pathologies fapaneng (ho electrolyte imbalance, lefu manyolo pelo, joalo-joalo).