Lithethefatsi 'k'halsiamo pantothenate': litšobotsi tse le ho sebelisoa moriana

asiti Pantothenic (litekanyetso li behoa foromo - lithethefatsi "k'halsiamo pantothenate") e ne e akarelletsa sehlopheng sa oa vithamine ea B. ena mafura, optically a sebetsang a mokelikeli, haholo qhibilihang ka har'a ka metsi, e habonolo khomaretse tlas'a bohato la mocheso, acid le alkalis.

asiti Pantothenic fumanoa lijo le e tsa maiketsetso ke microflora mala (Escherichia). Mora absorption ho kena maling 'me o etsoang ho makala ohle le lisele, e beha ka sebete, karolo e' ngoe ka myocardium, a liphio le mesifa ya marapo. 'Meleng, ka go tlhaolega acid e amanang le liprotheine' me e le karolo ea CoA (coenzyme A). thipitlo lihlahisoa tsa ea lithethefatsi "k'halsiamo pantothenate" excreted ka moroto le fumaneha mantleng. E tlameha ho ka boleloa hore palo ea acid e kgethile pantothenic ke kamehla a maholo ho feta hore e leng kena 'mele ka lijo. Sena ke ka ntlha ya go tswakana lona baktheria.

asiti Pantothenic ke karolo ea CoA, eo e na le likarolo tse tharo: ya masalla tiolamina, acid e pantothenic, 3-phospho-5adenozin-5-diphosphate. CoA ke elements ea bohlokoa ho metabolism, kopanelang papaling ea ho ea ka tšebetso ea ho Krebs potoloho ka tswakana tsa likokoana-hloko le ho kena moea oa lik'habohaedreite, lipids, glucosamine sebopeho, acetylcholine, acid e hippuric, porphyrins, joalo-joalo

Lithethefatsi "k'halsiamo pantothenate" - hanyenyane yellowish kapa o mosoeu phofo le tatso e babe, odorless, qhibilihang ka har'a metsi. ditharollo ea metsi ya thermally tsitsitse, empa ka potlako heletsa ha a pepesa ho acid e le a alkali. Ho lokisetsa meriana e hlahiswa e le matlapa a, phofo le tharollo ka vials.

Lona liketso tsa diokobatsi ho lokisetsa "k'halsiamo pantothenate" bontša ka mor'a acid e pantothenic fetoloa coenzyme A, eo e fana ka beta-ho kena moea, tse mafura acid e tswakana, decarboxylation oxidative, le ho fetola acid e pyruvic le ketoglutaric acetyl. Ho thusa absorption ea tsoekere ka intestine le, eketsa boemo ba glycogen ka sebete, normalizes boemo hormonal ba phelang, haholo-holo nakong ea bokhachane.

Ka khaello ea acid e pantothenic ka 'mele ke thibang hormona mosebetsi pituitary, adrenal tšoelesa le manyeme. The litsoelesa adrenal fokotsa boemo ba li-hormone steroid, e fana ka pigmentation tsa moriri le letlalo. boloetse tshilong ya dijo ka qholotsa dermatitis, letlalo depigmentation. liphetoho tse holofatsang a hlokomela ka ho litsoelesa le adrenal le dinama tse nyenyane tse ea methapo. Ba ile ba boela ka ba robehileng dilenaneo tšebelisano, mpefala lefu liphio, pelo, mala le mala. Lisosa e ka sehloohong ea haella a vithamine a lekaneng e ngata oa vithamine ea sena lijo, lefu mantle a, 'me tšebeliso ka nako e telele ea lithibela-mafu (sulfonamides, lithibela-mafu).

Ka sehloohong ea tleleniki lipontšo tsa ho hloka acid e pantothenic 'meleng - ho tepella maikutlo, ho ba le mokhathala, mokhathala, lefu la ho hlobaela, ho tšoaroa ke hlooho le ho opeloa ke mesifa, ho nyekoa ke pelo, letšollo, Flushing tsa letlalo setopong, duodenal seso. Ho haella oa vithamine ea fokotswa immunological hanyetsa ea phelang. Khahlanong le semelo sa ena, hangata haholo ho na le mafu a matšoafo.

hangata haholo, lingaka ho laela lithethefatsi "k'halsiamo pantothenate" bakeng sa molao oa tsamaiso ea dithulaganyo tshilong ya dijo. Amohela ka itse moriana o polyneuritis, paresthesia, neuralgia, la bronchitis, eczema, dermatitis, chesa, liso tsa ka maleng trophic, ho ima ho toxicosis, lefuba, hypothyroidism, pancreatitis, gastroduodenitis, joalo-joalo Medicine "k'halsiamo pantothenate" hantle-mameletse ka 'mele. Bakeng sa tsamaiso enteral ka 'na dyspeptic matšoao a, ke parenteral (a entoe nameng) - soreness.

Oversupply tsa khalsiamo (hypercalcemia) ka etsahala ka lebaka la ho ho se sebetse ea endocrine litsoelesa (parathyroid tšoelesa). Hypercalcemia e ngolisitsoeng ka batho ba hōlileng. hypercalcemia Clinic ka bontša cramps ka bofokoli kakaretso, tahlehelo ea takatso ea lijo, ka linako tse ling o ile a re le pipitlelano.