Lithethefatsi "Ofloxacin": mamello Testimonials. Litaelo bakeng sa ho sebelisoa tsa lithibela-mafu "Ofloxacin"

Ho lokisetsa "Ofloxacin" dikatlholo bakuli eo hangata e ntle, e emela moemeli loantsang likokoana ho tloha sehlopha sa fluoroquinolones sephara a manyenyane ea mosebetsi. Lithethefatsi ama DNA gyrase - sekhechana baktheria, ho fana ka supercoiling 'me ka hona botsitso ba libaktheria DNA (ka lebaka la destabilization tsa DNA Strand shoela'ng).

pharmacodynamics

Le bolela "Ofloxacin" - ya lithibela-mafu e atlehang mabapi le microorganisms tse hlahisang beta-lactamase, hammoho le ho itima lijo-hola atypical mycobacteria. Ho meriana ke tsa mamela, seo ho fetisisa libaktheria mob mobile-mpe, ho akarelletsa le microorganisms tse manganga ho methicillin le lithibela-mafu tse ling. Streptococci, enterococci, le Mycobacterium lefuba ba tšoauoa ka sa tsitsang susceptibility ho lithethefatsi "Ofloxacin". Reviews of lingaka li bontša hore ho phekola ba tšoaetso ea anaerobic bakoang ke peptostreptokokki, peptokokki le anaerobes a mang, lithethefatsi hangata thuso.

Pharmacokinetics

Holim 'a ho fumana moriana o ka absorption ho feletseng (liphesente tse 95) le ho itima lijo. Bioavailability - fetang liphesente tse 96. Kamano ea ho liprotheine lero la mali - karolo ea 25 lekholong. Ka mor'a lihora tse 'ngoe ho tse peli ka mor'a tsamaiso molomo oa mahloriso phahameng ka ho fetisisa ea finyelloa. Ho lethal dose-itšetlehileng ka: ho sebelisa e 'ngoe e milligrams tse makholo a mabeli, tse' nè kapa tse makholo a tšeletseng tsa mahloriso lithethefatsi ile latellana 2,5, 5 kapa 6,9 ug / ml tse.

tshebediso ya lijo ka ama absorption ea lehlakoreng la slowdown ya, empa ha ho na le phello bohlokoa ka bioavailability. Ho lokisetsa "Ofloxacin" - ya lithibela-mafu ho ba le bophahamo ba modumo e khōlō ea kabo (lekholo lilithara), e le hore ho lokisetsa tsamaisoa ke hoo e ka bang palo e feletseng le kenella ka hare ka bolokolohi ka lisele tsa tsona li. The concentrations phahameng ka ho fetisisa ke ea lisele, maro a 'mele le ho makala: ka lisele tsa tsona li (macrophages alveolar, leukocytes), bonolo dinama tse nyenyane tse, letlalo, lesapo, tsamaiso matšoafo, makala a la pelvic le ka mpeng cavity, mathe, prostatic maro, moroto, bile. The hantle moriana o le kenella ka hare ho placental le mali-boko mokoallo, e secreted tloha lebese, 'me cerebrospinal mokelikeli kena ka bao e seng ruruhileng le ruruhileng lera la boko (ea 14 lekholong ho 60).

About 5 etsang liphesente tse ea lithethefatsi e metabolized ka sebete le ho theha dimetilofloksatsina le N-oxide e ea ofloxacin. Ho sa tsotellehe hore ba lethal dose halofo bophelo bo pakeng tsa tse 'nè le halofo ho lihora tse supileng. Khumo sa fetohe lithethefatsi ka palo ea liphesente tse 75-90 ea liphio, ka palo ea liphesente tse 4 - ka bile le. ba etsang liphesente tse ka tlase ho 20 tsa rengwa extrarenal. Mora lethal dose e le ba se nang balekane ba milligrams tse makholo a mabeli ba moemeli e lemohuoa ka moroto bakeng sa lihora tse 20-24. Tabeng ea e amanang le sebete kapa renal excretion ka liehisa. Ha dialysis e tlosoa ka liphesente tse 10 ho ea ho tse 30 tsa meriana.

bontšang bakeng sa

Ka mafu a tšoaetsanoang le a hlabang bakoang ke microorganisms tse sa tšoaneng, ho bontšitsoe sebelisoa moriana o "Ofloxacin". Reviews ba tlalehile hore ke ntho e ntle haholo bakeng sa tšoaetso ea matšoafo pampitšana (serame sa matšoafo, la bronchitis), e ka holimo ho hema pampitšana (mecha ea phatlalatso nattokinase, sinusitis, laryngitis, pharyngitis). Abela lithethefatsi bonolo diso dinama tse nyenyane tse, manonyeletso, masapo, letlalo, biliary pampitsana pampitšana mosese (urethritis, cystitis), a liphio (pyelonephritis), cavity mpeng, genitalia (orchitis, colpitis, epididymitis), makala pelvic (salpingitis, prostatitis, cervicitis, endometritis, oophoritis, di-parameter).

Hape e atlehang lithethefatsi bakeng sa ureaplasmosis, chlamydia, qhoshola. Sebelisa bakeng sa thibelo ea mafu a tsoaetsanang a bakuli ba mafu a ea boemo ba mmele (ho akarelletsa le neutropenia le).

The litekanyetso li behoa foromo. sebopeho

Ho lokolloa ha moriana o ke ka mokgwa wa lera tšoeu kapa hoo e ka bang tse tšoeu filimi-a tlotsitsoeng matlapa biconvex sebopeho pota. Sefapano sectional bonahaleng le dikarolo tse peli, e 'ngoe ea tse nang le bb yellowish. Active karolo sebetsang sebakeng sa hae e le ofloxacin. Letlapa le nngwe tse boima ba 200 kapa 400 mg,. Minor metsoako tse primelloza (croscarmellose sodium), microcrystalline selulose, Aerosil (colloidal silicon e dioxide e), silica titania, povidone, hydroxypropyl methylcellulose (hypromellose), talc, magnesium stearate, nhua polyethylene glycol 4000 (macrogol). A sebelisa monyetla o moholo oa lithethefatsi "Ofloxacin" - theko. Tablets nang 200 mg, ea boleng bo le mafolo-folo ke karolelano ea li-ruble 16-20 ka likotoana tse 10, 'me ba hore na le 400 milligrams ofloxacin, e tla chelete ka 50-55 li-ruble ka likotoana tse 10.

"Ofloxacin" moriana. Litaelo tsa tšebeliso

Tablets lokela ho noa pele kapa ka mor'a lijo. Ba lokela ho metsoa ka kakaretso, ntle ho hlafuna, 'me noa metsi ka bongata tse nyenyane. litekanyetso li behoa lokela ho khetha le batho ka bomong ho itšetlehile ka ho tiea ha lefu lena, ho diriswa ea tšoaetso, mokuli a se boemong bo akaretsang, mosebetsi a liphio, sebete, 'me libaktheria li nahanela.

E le busa, ho phekola "ofloxacin" o entsoe ka matsatsi a supileng ho tse leshome. Batho ba baholo ba letsatsi le letsatsi tseo ke li behetsoeng noa tse makholo a mabeli, milligrams makholo a tšeletseng habeli ka letsatsi. The lethal dose ka eketsehile ho milligrams robeli tabeng ea tšoaetso e tebileng, kapa haeba ba le mamello ke nona haholo. lethal dose A ya milligrams a mane ka nkoa hang-hang, ka go tlhaolega hoseng.

Bakuli ba nang le mosebetsi phytoteratology renal hang a ke ke a nka milligrams fetang makholo a mabeli tsa ea lithethefatsi, e lethal dose lebetsoeng le letsatsi ka kholofalo e amanang le sebete - milligrams makholo a mane. Ka mor'a hore ho nyamela ha matšoao a le tlwaelegileng a ea mocheso, esita le bakeng sa matsatsi a mabeli kapa a mararo lokela ho tsoela pele phekolo.

Le litla-morao. Testimonials

Sa bakuli bohle ba lithethefatsi "Ofloxacin" hantle mameletse. Reviews of batho ba bang ba na le litaba tseo lithethefatsi baka hlooho e opang, ho nyekoa ke pelo, ho hlatsa, letshollo, ha thothomela hohle, shoohlo ea lipheletsong. Ka lehlakoreng la tsamaiso tshilong ya dijo ka ntshetsa pele e le bohloko mpeng, gastralgia, bloating, cholestatic nyooko, ho ipolaisa tlala, hyperbilirubinemia, pseudomembranous enterocolitis, 'me tsamaiso ea methapo - ho hloka ho tsamaea, cramps, litoro le matla haholo, liphetoho psychotic, pherekano, matšoenyeho, pherekano, phobias, lipono, ho tepella maikutlo.

Ho phaella moo, ho na le kotsi ea ho tlōla ea tsamaiso dilenaneo (arthralgia, tendonitis, myalgias), le hlaphohetsoe likelellong (mafu a tatso, 'mala pono, ho utloa, ho leka-lekana, monko), tsamaiso ea vascular le pelo (phokotso ka khatello ea mali, tachycardia), letlalo (dermatitis, ntlha hemorrhage, papular lekhopho), ya hematopoiesis (thrombocytopenia, khaello ea mali, leukopenia). Ka mor'a ho amohela "Ofloxacin" lithethefatsi (ulasan pelanggan netefatsa ena), maemong a mang ho bonahala itchy letlalo, bronchospasm, urticaria.

Contraindications

Fumana moriana o thibetsoe mamellane ofloxacin le tse ling tse derivatives fluoroquinolone, tabeng ea khaello ea tsoekere-6-phosphate dehydrogenase, sethoathoa, diso tsa tendons e, fokotsa inkela ka mahahapa monyako. Ho phaella moo, u ke ke ua nka lithethefatsi bakhachane le lactating "Ofloxacin", bana ba ka tlaase ho lilemo tse leshome le metso e robeli. Ka ho lokisetsa hloko e hlophisitsweng bakeng sa mafu a ho potoloha ha mali bokong, bokong vascular atherosclerosis, ho hloleha renal ho sa foleng CNS diso tlhaho manyolo.

Moriana o "Ofloxacin" ka ureaplasma ka. Reviews

The ntho e ka sehloohong ke hore batho ba re, sebelisa sehlahisoa sa - e le phello ea hae kapele. Bakuli ba tlaleha hore seo se sa hlokomeleheng se ka letsatsi la boraro kapa la bone. Empa e ke ho hlokahala hore ho lemosa hore sena ha se bolele qala ho ea pheko. Tseo bakuli ba khaolitse ho noa matlapa a, ho se na ea ka thupelo feletseng, ka nako eo hape nang le phihlelo le matšoao ureaplasmosis, hobane libaktheria li e-s'o ka ho feletseng felisitsoe.

lemosa

Ha serame sa matšoafo halefisoa ke nyumonia, lithethefatsi thuso. Hape, ho e sa bontša bakeng sa kalafo ya tonsillitis hlobaetsang. Ho ke ke ho hlokahala hore ba khaotse ho ea lithethefatsi ha ka semelo sa kenoa hae ba e itsoara joang alejiki, ho CNS ho hloka taolo, pseudomembranous colitis. Basali ho sebelisa le bolela "Ofloxacin", ho e sa kgothaletswa ho sebelisa tampons, hobane tabeng ena ho na le kotsi ea ho ba le thrush eketseha.