Lithethefatsi "Hydroxyzine": litaelo bakeng sa ho sebelisoa, analogs le ulasan pelanggan

Diphenylmethane derivatives tsa ntho e ke mokhoa oa ho "Hydroxyzine". Mosebedisi kopo e bolela hore ntho ke e tsoeu e le phofo e thumisehileng, qhibilihang ka har'a ka metsi le odorless. dikgerama 374,9 ka mole ke boima ba 'mele ea limolek'hule tsa kompone.

Clinico-diokobatsi sehlopha

Lithethefatsi o sedative, anxiolytic sebediswa. Ena e hlalosa phello inhibitory ka mosebetsi oa itseng dibopeho subcortical tsa tsamaiso ea methapo e bohareng hammoho le emisang bohato ka bohareng H_1-histamine le limithara-cholinergic receptors.

"Hydroxyzine" analogues lithethefatsi ba le robatseng phatlalatsa le mosebetsi o bonolo anxiolytic. Ba le phello e susumetsang ka bokhoni dikopanothutano, ntlafatsa tlhokomelo le hlooho. Senohi ho itšetleha le ho lemalla ha etsahala ka mor'a sebelisoa ka nako e telele ea syndrome, e sa a hlokomela. Hape o ile a bontša anticholinergic, antihistamine, bohato antispasmodic. "Hydroxyzine" lopollang spasms tsa mesifa le boreleli, ka tsela eo ho etsa hore bronchodilatory le litla analgesic, a nang le tsona bohato antiemetic le e leka-lekaneng inhibitory ama secretion gastric. . Hives, dermatitis, eczema, ho hlohlona, joalo-joalo decreases nakong phekolo e bolela "Atarax" (hydroxyzine - a sebetsang a ntho).
Tataiso e bolela hore robatseng e fihlellwa, hangata ka hare ho metsotso e 10 ho 45 ka mor'a a e-ja (ho itšetlehile ka sebōpeho sa moriana), khahlanong le histamine - hora e 'ngoe ka mor'a a e-ja. Bakuli ba nang le lefu sebete, le phello antihistaminic ka lebeletsoe ka hare ho lihora tse 96.

Ha tšoauoa mutagenic le carcinogenic ketso ya moriana.

Pharmacokinetics

Ha ingested lithethefatsi e ka potlako ananelang pampitšaneng gastrointestinal, C_max moo ka lihora tse peli. Ho lokisetsa "Hydroxyzine" feta ka placenta le mali-boko mokoallo (tekanyo ea mahloriso ka lisele fetal moholo ho feta ka lisele tse 'mè). Ka tshebetso ya ho e amanang le sebete metabolism thehoa cetirizine - the metabolite khōlō. Boleng T_1 / 2 ho sa tsotellehe lilemo tsa mamello le ka ba 7 lihora tse bakeng sa bana ba lilemo li dilemo 2-10, lihora 20 bakeng sa batho ba baholo, lihora 29 bakeng sa batho ba hōlileng le batho ba hōlileng; bakuli ba nang le lefu sebete ka eketsehile ho lihora tse 37. felisoa e etsoa ka nako e ngata ke liphio (0,8% foromo ka eona qalong).

ho bonahala

"Hydroxyzine Hydrochloride" le sebelisitsoe ho:

• felisa ho tšoenyeha le ho hyperexcitability ea tsamaiso ea methapo ea kutlo;
• nakong a khaotsa ho tsuba ka batho ka bomong ba nang la ho itšetleha joala;
• phekolo kalafo ea mafu a psychoneurotic;
• e le karolo ea kalafo akaretsang ka nako postoperative 'me ka mor'a ba bang ba tsoa likotsi;
• premedication;
• ho fokotsa khatello ea kelello ka hare, ho tšoenyeha generalized, dithulaganyo phetoho hlaphoheloa, ea ho phekola mafu a systemic;
• ho felisa matšoao a eczema, itchy dermatosis, urticaria, atopic dermatitis;
• bakeng sa bohato antiemetic bontša.

Contraindications ho moriana "Hydroxyzine Canon"

Reviews of lingaka li bontša hore lithethefatsi e sa kgothaletswa ho fumana:

• bakuli ba nang le glaucoma;
• ea tšoelesa ea senya hypertrophy (ea tšoelesa ea senya);
• bakuli eo ho eena ho e eketsehileng mosebetsi inkela ka mahahapa;
• bakuli ba myasthenia gravis;
• bakuli ba fumanoa renal le e amanang le sebete ho hloleha;
• bakuli ba nang le 'dementia'.

moriana o contraindicated ka se:

• bakhachane;
• bakuli ba porphyria;
• nako ea kanyeso (nako ya kalafo lokela ho lahla lebese kanyeso mè);
• alejiki liponahatso tsa molao motsoako (ka maemong tseo moo pele e neng e tšoaea hypersensitivity ho tse ling sehlahisoa cetirizine, aminophylline, piperazine kapa ethylene diamine);
• nakong ea mosebetsi o boima le pelehi.

About litla-morao

Bakuli ba ka 'na le bothata ba ho ke boroko, keteka kakaretso bofokoli, ho tsekela' me hlooho e ka e le qalo ea phekolo lithethefatsi "Hydroxyzine". Reviews of bakuli tšoaroa ka moemeli ena, re liphello tse latelang lehlakoreng:

• kulisa, palpitations, ho nyekoa ke pelo;
• mosese tshegetsa le go tlotla, le pipitlelano;
• omile tsa lera la bonahalang mucous, e ile ea eketseha ho fufuleloa;
• thothofatsang Pono (mohlomong ho tlōla tsa bodulo);
• theola khatello ea mali, e ile ea eketseha mosebetsi sebete potlakisang tsebetso ea lik'hemik'hale;
• ka 'na ba bronchospasm.

seoelo haholo ponahalo sethoathoa, tremor le disorientation, ataxia, paradoxical tlhotlheletso le eketsehileng mosebetsi dilenaneo ka tšebeliso ea lisebelisoa.

overdose

Ntho ea bohlokoa ho bitsoa gag reflex kapa mpeng e hlatsoa ka overdose ea lithethefatsi "Hydroxyzine". Litaelo bakeng sa ho sebelisoa tsebisa hore maemong a mang ho hlokahala tlhokomelo mesebetsi mokuli a se bohlokoa, ho qaloa ho benzoate sodium, caffeine, norepinephrine, 'me esita le baemeli mali, li etsoa ka mehato tsohle ho hlokahala hore ho ho boloka ea ka tšebetso e nepahetseng ea' mele. antidotes itseng sesebelisoa sa na, hemodialysis e se fosahetse.

Hangata ka ho fetisisa, liphello tsena ke reversible kapa matšoao a bona nyamela ka mor'a litekanyetso li behoa ea letsatsi le letsatsi ea hlaoloa.

litekanyetso li behoa

moriana o laolwa ka molomo kapa ka ho ente intramuscular. The lethal dose ho itšetlehile nosologies, lilemo tsa mamello le mokgwa oo lithethefatsi Ho lokolloa "Hydroxyzine".

Litaelo bakeng sa ho sebelisoa ho bontša hore bontshang matshwao kalafo bakeng sa lefu ho tšoenyeha, batho ba baholo kgothaletswa ho noa la mg, 25 ho ea ho tse 100 tsa boleng bo constituent motšehare. Ka ho fetisisa e atisa ho sebelisoa litekanyetso li behoa ea 12,5 mg, hoseng le ka lijo tsa motšehare le 25 - mantsiboea.
Bongoaneng, preoperatively sebelisa ho 1 mg, ka ho ya ka lik'hilograma tsa boima ba 'mele ka letsatsi le mantsiboea pele le metsotso e 60 pele ho buuoa.

Ka morero oa ho premedication e laolwa ho batho ba baholo "Hydroxyzine" ka lethal dose ea la 50-200 mg, ea lithethefatsi ka molomo kapa ka mokgwa wa liente intramuscular ea 1.5-2.5 mg, ka ho ya ka lik'hilograma tsa boima ba 'mele le mamello laolwa hora e' ngoe pele ho buuoa.

Ka morero oa ho ea liphallelo e ba ho hlohlona litekanyetso li behoa e atlehang ke ho tloha 25 ho ea ho 100 mg, ka 3-4 tekanyetso aroloa.

Bana ba tloha ka ba lilemo selemo se le seng ho 6 lethal dose ea ha sa feteng 1-2.5 mg, ka ho ya ka lik'hilograma tsa boima ba 'mele ka letsatsi ka tekanyetso aroloa.

Ka e tšoanang dosing Melao ea bakeng sa bana ba ka tlaase ho lilemo tse lilemo tse 6 e ka abeloa ho 1-2 mg, ka ho ya ka lik'hilograma tsa boima ba 'mele motšehare.

Palo e kahodimodimo ea letsatsi le letsatsi lethal dose nkoa e le 300 mg,. Palo e kahodimodimo le 'ngoe lethal dose - 200 mg,.

Ba Hōlileng qalo ea phekolo khothalletsa halofo litekanyetso li behoa.

Sebete le ho hloleha liphio hloka khalemelo ea litekanyetso li behoa ea ea lithethefatsi "Hydroxyzine".

Tataiso e lemosa hore ho se finyella palo e kahodimodimo ho phekola le phello tharollo e potlakileng e laolwa intramuscularly, tebileng 50-100 mg, ka ho ya ka lethal dose 'ngoe. E kgothaletswa dithekeniki tsamaiso ea lithethefatsi bakeng sa ho lihora tse 4-6.

Ka psychiatry, moriana e sebelisoa ka litekanyetso li behoa ea 300 mg, ka matsatsi a. Ka nako ea phekolo ena ke libeke tse 4.

Tabeng ea ponahalo ea litla-morao tse kang bofokoli, ho otsela, ha e khaotse ho ka mor'a matsatsi a seng makae, lethal dose lokela ho tsa fokotswa.

mehato precautionary

Ha qaloa ho "Hydroxyzine" ho tloha "Adrenaline" tšoarelle ka tlase e atlehang.

Lithethefatsi na le phello e eketsa ka phello sedative tsa tlhahiso ea lithethefatsi analgesics letoto la lihlooho tse, lino tse tahang, ea kelello, barbiturates, lithethefatsi sebelisoa ka sepheo sa ho lithethefatsi hypnotic le tse ling tse hore depress CNS mosebetsi.

Sa kgothaletswa kopo kopanetsoeng ba ntho kapa holinoblokatorami le Mao inhibitors.

Ha ho kopantswe le mokhoa oa ho ho nka phenytoin anticonvulsant le phello decreases ho tloha moketeng oa lijo tsa qetellang.

Rateheng tsoa hong sebelisa lithethefatsi le blockers cholinesterase.

A le phello e la eketsa lero la mali mahloriso ea lithethefatsi ba ka 'na ba sebeletsa kopo lona le inhibitors tsa enzyme sebete.

Tsoa hong kalafo le mahlahana a tse thibela metsoako mosebetsi oa CNS, kapa le holinoblokatorami hloka litekanyetso li behoa phetoho.

Ka hloko haholo e lokelwa ho bewa bakuli ba nang le ho sekamela ho fibrillation kapa ho sebelisa antiarrhythmics, hammoho le ho batho ba teng bakuling ba ua tsoaroa ke ho liponahatso convulsive. phekolo e ke contraindication ho tšebeliso ea lino tse tahang. Haeba ho hlokahala, boitšoaro liteko ka kulisoa baeti ba fihlelang ho "Hydroxyzine" ho hlakola ho fihlela ho matsatsi a 5 pele ho hlahloba ka ho lokiselitsoe mosebetsi. Hlokolosi ha ba sebelisa lithethefatsi 'me taolo ya koloi nako bakhanni le bakuli, diprofesheneng hore hlokang phahameng mahloriso.

E lokela ho jere hopola hore tshebediso ya injectables ke feela khoneha ke ente intramuscular. Subcutaneous ente ea koloi kapa ho kenella ka hare tsa bobeli ka lijaneng kgolo ka baka tšenyo e dinama tse nyenyane tse.

Therapy sesebelisoa sena ka vyzyvavt diphetho ba bohata teko prick.

Le dipehelo tsa tšebeliso le poloko

Hoa hlokahala ho ba teng e tlamang ea lengolo la ngaka bakeng sa lithethefatsi "Hydroxyzine".

Litaelo bakeng sa ho sebelisoa e re liforomo tsa molomo oa ea lithethefatsi ha ba bolokwa ka lilemo tse fetang 5.

"Hydroxyzine". Testimonials

Ka bana, tšebeliso ea chelete ka tlas'a hyperactivity, fokotswa a lebisa tlhokomelo sepane thusa ngoana hore a be sebete, tsepamisa maikutlo le mamela ka hloko, felisa feto-fetoha. Ka nako e tšoanang ea ho phekola ba lithethefatsi "Atarax" ( "Hydroxyzine") litaelo bakeng sa ho sebelisoa tiisetsa hore mosebetsi le mafolofolo ea ngoana e lula e le 'ngoe. litla-morao tse ka seoelo.

Ho ea ka dipolelo tsa bakuli, ho sebelisa ka itseng Maemong a "Hydroxyzine" (analogues ya moriana), e latelang e le hore a ke e nang le khutso le ho itšepa ho ka tekanyo e khōlō ho feta lithethefatsi tse ling tse ngata. Tšohile litlhaselo tse le lefu la ho hlobaela ntho e khothalletsa batho molemo robala le ho robala e hlaphohileng. Leha ho le joalo, ho tlosa moriana matsatsi a seng makae pele ba e ba nyahamisa boima ka tshebetso ya ho robala, empa, ka molao-motheo, phello ea phekolo e khothatsa haholo.

Theko ea lithethefatsi e

Reka lithethefatsi "Hydroxyzine" counterparts, e le karolo ea eo e na le hydroxyzine, e ka ba famasi ka lengolo la ngaka. Price ke 270-300 li-ruble ka matlapa a 25 ea 25 mg,.

"Hydroxyzine". synonymes

Synonymes "Hydroxyzine" ke: "Hydroxyzine Canon", "Atarax", "Masmoram", "Ateraks", "Hydroxyzine", "Hydroxyzine Hydrochloride", "Alamon", "Duraks".