Hypothalamic lokolla hormone

Ho lokolloa-hormone tse neurohormone batho hore e tsa maiketsetso hypothalamic khubu. Ba thibela metsoako (statins) kapa susumelletsa (liberiny) tlhahiso ea Tropic pituitary-hormone. Ho activates litsoelesa le endocrine, 'me ho na le molao oa tsamaiso ea ho lokolloa ha li-hormone. Likarolong e phahameng ea tsamaiso ea bohareng methapo le tsamaiso endocrine ba haufi-ufi amanang le ka lebaka la ho li-hormone lokolla.

mosebetsi hypothalamic

Ngoe ea likarolo tsa bohlokoa tsa tsamaiso ea endocrine nang le boikarabelo bakeng sa tlhahiso ea li-hormone - the hypothalamus. Hlahisoang ke ho hypothalamus dintho di-hormone amehang dithulaganyo tshilong ya dijo ea 'mele.

Ka hypothalamus le na le lisele tsa methapo ea kutlo tse netefatsa ho hlahisa lintho tse hlokahalang, 'mele o hloka ho tshebetsong tloaelehileng. lisele tse tsena li bitsoa neurosecretory. mosebetsi oa bona - ho fumana linaoa hore fetisetsa likarolong tse fapaneng tsa tsamaiso ea methapo. likarolo ho itšehla thajana le hlaha ka synapses aksovazalnye.

Hlahisoang ke hypothalamic lokolla hormone, kapa ha ba ntse ba ba bitsoa ka tsela e fapaneng, statins le liberiny, ke tsa bohlokoa bakeng sa tshebetso e tloaelehileng ea pituitary tšoelesa. Ka tlhaho bona lik'hemik'hale, ba peptides. Ka lebaka lik'hemik'hale le methapo ea kutlo takatso e tswakana bona, ba ile ba ba isoa ho ea mali ke pituitary hypothalamic-pituitary tsamaiso.

tlhophiso hormone

Nahana ka ho fetisisa tsebahalang lokolla hormone:

• Inhibiting ea secretion ea pituitary mosebetsi - ke somatostatin melanostatin, prolaktostatine.
• Stimulant - re bua ka melanoliberine, prolaktoliberine, folliberine, lyuliberine, somatoliberin, thyrotropin-ho lokolloa hormone, gonadotropin-ho lokolloa hormona le corticotropin.

dintho tsena, kapa ho ena ba bang ba bona, ka le kakanyo feela e hlahisoang ke 'mele tse ling, e seng feela ho hypothalamus (mohlala, manyeme).

Statins le liberiny

Ea ka tšebetso ea pituitary tšoelesa e ka ho toba e itšetlehileng ka bona. ba boetse ba na le tšusumetso ea ka tšebetso ea ho litsoelesa endocrine pheriferale:

• thyroid;
• mae a bomme ka banana ba;
• testes ka ba batona.

Statins le liberiny eo molemo ka ho fetisisa tsejoa ke tsena:

• dopamine;
• GnRH (lyuliberin, folliberin);
• melonostatin;
• somatostatin;
• tireoliberin.

The secretion ea luteinizing hormone ea le li-hormone follicle-Stimulating ea pituitary GnRH fana.

Ka mosebetsi oa androgen ka banna hape ama GnRH, kenya letsoho hore ho e leng keketseho ea mosebetsi peō ea botona le boemo ba libido.

Le basali neurohormone le boikarabelo ba ho ea matsatsing, ka tjhelete e ya li-hormone fapana le mohato oa potoloho ea eona.

Lekaneng tlhahiso ea ho lokolloa hormone hangata e etsa hore ho kgaolela basadi thari le ho hloka matla.

Litšobotsi tsa li-hormone

hormona Corticotropin le boikarabelo ba ho le maikutlo a ho tšoenyeha, e hlahisoang ke hypothalamus le. Sena ke 'ngoe ea bohlokoa ho lokolloa Ntlha e, a sebetsa hammoho le li-hormone le pituitary le litla bona ka litsoelesa le adrenal. Batho ba nang le ho hloka li-hormone ena hangata e le bothata ba ho kgatelelo ya madi, le adrenal insufficiency.

GnRH - le li-hormone hore kgothaletsa ho hlahisa gonadotropins - e boetse e le sehlahisoa sa hypothalamus le. E boetse e bitsoa gonadotropin-ho lokolloa hormona.

Tshebetsong tloaelehileng ea makala ho ikatisa ke ke a etsa ntle le GnRH. Ho li-hormone ena ea ikarabellang ka tsela e ea tlhaho ea potoloho ea matsatsing ho basali. Ka ho ba le seabo hae o beha tshebetso ya ho le nonofo ya mmele le ho lokolloa ha leheng. hormona Sena ke le boikarabelo ba ho libido (ho kopanela liphate ka koloi). Ha ho na le lekana tlhahiso ea li-hormone e ka hypothalamus ka basali ba atisa ho ba ho kgaolela basadi thari. Eng hape ba lokolloa-hormone?

somatoliberin

Ho fetisisa ka potlako lokolloa ka bongoaneng le lilemong tsa bocha. Tšobotsi lona se seholo ke tshebetso ya ho tlwaelegileng a ea litsamaiso ea 'mele ea kgolo ya lekala le. From tlhahiso ea lona e itšetlehile ka ntshetsopeleng e feletseng le sebopeho sa ngoana. Lekaneng tlhahiso ea hormone tloha hypothalamus le ka etsa hore dwarfism (dwarfism).

Prolaktoliberin

ntshetsopeleng hae ho fetisisa a sebetsang a etsahala emara 'me ho pholletsa le nako ea ho fepa' mè oa ngoana eo. Sena Ntlha e lokolla normalizes tlhahiso ea prolactin, eaba ba etsa ducts tsa litsoelesa le mammary.

Prolaktostatin

Prolaktostatin e bua ka sehlotshwana tsa statins hlahisoang ke hypothalamus le, ke eena ea ikarabellang bakeng sa thibelo ya prolactin.

Ke prolaktostatinam kenyeletsa:

· Dopamine;

· Somatostatin;

· Melanostatin.

ketso ea bona e ka sehloohong o ikemiseditse ho hatella-hormone le Tropic ea pituitary le hypothalamus.

Melanotropin,-ho lokolloa hormona

Ka tshebetso ya ho melanin pigment le karohano ea lisele ama melanoliberin. O ile a boela o nka khato ka boemo ba leholimo ba DWP pituitary.

Litšusumetso neurophysiological boitšoaro. E sebediswa bakeng sa ho tlosa ho phekola e re tepelletsang le parkinsonism.

Thyrotropin-ho lokolloa hormona (TRH)

Ke li-hormone thyrotropin-ho lokolloa ba hypothalamus le hape e sebetsa thyroliberine. E khothalletsa batho ho hlahisa li-hormone tsa anterior pituitary thyritropic.

Ka tekanyo e nyane susumetsa tshebetso ya ho prolactin. Thyroliberine kgothaletsa ea mahloriso ea thyroxine maling.

CNS na le tšusumetso e matla ka le thulaganyo ya tlhahiso ea li-hormone. Bakeng sa tlhahiso ea neurohormones ba na le boikarabelo neurosecretory seleng ea taolo tsamaiso.

mesebetsi Basic liberinov

hypothalamic ena lokolla-hormone. Ho phetha mesebetsi ya bolaodi. GnRH normalize ea ka tšebetso ea tsamaiso ea ho ikatisa tsa basali le banna.

Ba na le boikarabelo bakeng sa ho ikatisa ea follicle-Stimulating Hormone le ama ho sebetsa ha ho testes le mae a bomme.

Joalo karolo e lyuliberin, e fetolela ikarolang phello ovulation, eaba ba etsa le monyetla fetal kemolo.

Basali ba iphapanyetsa bophelo ba e haufi-ufi, le lyuliberin folliberin hlahisitseng ka bongata lekaneng.

Ho boetse ho na le mabaka a ho lokolloa e amanang le kabelo karolelano ea hypothalamus le, empa mabapi bona ho pituitary anterior lisele tse pituitary le e-s'o ile a ithuta.

Agonists lokolla hormona: lithethefatsi

Joalokaha ho se ho boletsoe, li-hormone tsena hlahisoang ke hypothalamus le. Ha e se e batlang hore a susumetse le mae a bomme, ka mohlala pele Tsamaiso IVF, sebediswa agonists kapa corticotropin lokolla hormona analogs. Ke hore, ba na le 'mele le phello e tšoanang le ea li-hormone tsa lona.

Empa menyetla a itšoare e bohloko ka lehlakoreng la 'mele e motšehali. Sena se etsahala ka lebaka la ho maemo tlaase estrogen bananeng. Liphello atileng ka ho fetisisa li akarelletsa:

• hlooho;
• ka tsela e feteletseng ho fufuleloa;
• chesang mahlaseli;
• bosaling omile;
• feto-fetoha;
• ho tepella maikutlo.

Lithethefatsi li sebelisoa ka tsela e latelang:

• "Diferelin" ke maiketsetso decapeptide manaka tsa li-hormone tsa tlhaho ho lokolloa.
• "Dekapeptil" e le karolo ea triptorelin ka, e manaka maiketsetso tsa GnRH. The halofo bophelo nako e telele. Sebelisoa hangata bakeng sa ho insemination maiketsetso.
• "Lyukrin depo" - leuprorelin. Ho na le-ba khahlanong le estrogen bananeng,-ba khahlanong le androgenic le hantle, liphekolo endometriosis, li-hormone itshetlehile lihlahala - kankere ea tšoelesa ea senya e, fibroids uterine. "Lyukrin depo" ho fokotsa ea mahloriso ea testosterone banna, estradiol ka basali, ho phaella moo, thibela pituitary incretia FSH, LH.
• Phello ea lithethefatsi butle-butle tsosolosa ea secretion fisioloji hormone.
• 'Zoladex' - maiketsetso manaka tsa tlhaho li-hormone-ho lokolloa hormona (LH). Atisa ho sebelisa ka IVF. Ho fokotsa ea mahloriso ea estradiol maling, o hlahellang ka lebaka la hatelloang tsa LH secretion ea anterior pituitary.
  

Re ile ra buisana ka litokisetso agonists lokolla hormona.

ba khahlanong le lōna

Ho tloha ha ho amohela ho lokolloa hormona agonists eketseha ka mokhoa o fetisisang estradiol ka 'na la hlaha botsoalle lokolloa ha luteinizing hormone ea. Sena se etsa hore ovulation pele ho nako le ho timetsoa ha mahe. Ho qoba sena, ho ba khahlanong le lōna lokolla sebelisoa li-hormone. Ka lebaka la liketso tsa bona e ka re susumelletsang ho pituitary tšoelesa hape. Popelo hyperstimulation lefu ha iponahatsa, empa ho ke ke hangata ho joalo ka lebaka la ho sebelisoa nako e telele GnRH agonists. Ba tsamaisoa fela matsatsi a mahlano ho tloha qalong ea kopo ya follicle hlasimollang-hormone.

Ho fumana phekolo e atlehileng, tsohle-morero oa ka litokisetso lokela feela hore e be setsebi.