Asiti Phosphatidic. Tswakana le bohlokoa 'meleng

From pono ea sebopeho lik'hemik'hale, acid e phosphatidic ke phospholipid bonolo.

ntho ena ke e 'ngoe ea liketsahalo tsa bohlokoa tsa phosphoglycerides metabolism ka vivo.

sehlopha sena sa dintho e eloa hloko haholo ka ho ithuta mesebetsi pontšo ea metsoako lik'hemik'hale.

Ho fihlela joale, ho fihlela ho ea qetellong ha ho hlake le maqhama tsohle ka metabolism tsa acid phosphatidic, ka ho khetheha, e ntse ha tšohloa taba ea hore mochine oa dikgokelo ya data pontšo phetiso, hammoho le ka ho ba teng ha acid phosphatidic ionophoric thepa.

Tswakana ea acid e phosphatidic

Phosphatidic acid e sebopeho e susumetsoa ke phospholipase D. sehlopha sa ena ea enzyme e na le karolo ea itlhommeng pele ka ho e tswakana ea acid phosphatidic. E le e batlang e-ba ea nakoana lik'hemik'hale komponeng, o ile ntho tlas'a tšusumetso fosfogidrolazy hydrolysed ho diglyceride (by dephosphorylation itsoara joang ka).

Ha ho kopana le e tšoanang potlakisang tsebetso ea lik'hemik'hale acid e phosphatidic ka le fetohe le diacylglycerol, e etsang ka potoloho ea skeletal liphetoho activator mosebetsi oa potlakisang tsebetso ea lik'hemik'hale le protheine kinase C.

Tswakana ea acid e phosphatidic etsahala adipose dinama tse nyenyane tse. tshebetso qala ka rasiti ka adipocytes (adipose lisele tse dinama tse nyenyane tse) mafura acid thehoa ka hydrolysis ea mafura (haholo-holo, le tlaase haholo segokanyipalo lipoproteins). Ka hare ka seleng, sebelisana le glycerol-hut-phosphate, acid tse mafura a sokoloha pele ho acid e lysophosphatidic, ho tloha eo e ile ea thehoa acid e phosphatidic.

Moralo thehoa therefrom glycerophospholipids phosphoric nang litlhaka kahare ea acid tse mafura, glycerol, 'me naetrojene-e nang le anions.

Meaning of acid e phosphatidic

Ho ile ha fumanoa hore e acid e phosphatidic ke seo ho thoeng ke a hoehla dikgokelo, ke hore, tseo tse ka mosebetsi wa intermediaries ka phetiso ya tlhahisoleseding litseleng le a bontsa ho. Ka ho khetheha, ke kgokahanyo senotlolo ka phetiso ea ka matshwao a medumo tsena liseleng dimela:

• cytokinin;
• osmotic o nang le boleng ba ka ntshetsopele ya karabelo lisele ho mofuta ona oa khatello ea kelello.

Nakong ea liteko ho ile ha bontša hore boemo ba motsoako ka lisele tse o ile a pepesa ho dimela phelang lintlha pathogenic eketsa haholo. itšoara joang Sena se etsa hore:

• Osmotic khatello ea kelello.
• Tlaase le dithemparetjha.
• Phello ea metsoako e itseng a sebetsang a ba le hlahang ho yona meroho (phytohormones).

Kahoo, ho ka etsa qeto ea ho nka karolo ha acid e phosphatidic le metabolites lona ka liphetoho tse rarahaneng le boikarabelo ba ho tlwaetsa ba phelang ho maemong a sithabetsang.

Ho feta moo, ho tsejoa hore ea acid e phosphatidic ke habohlokoa bakeng sa ho tsamaisa ba protons le itsoara joang ka tsa ions k'halsiamo ka lera ea methapo ea kutlo 'me likhoele mesifa. Ka lebaka leo, acid e phosphatidic le hape Isang mosebetsi ionophore (khetha: bakeng sa ions k'halsiamo le protons).

mochine transduction

Le hoja morero oa asiti phosphatidic fumanoa ka kotloloho mokhoa (mochine) tsa phetiso ea pontšo ntse e phehisanang khang le hloka ga tlhaloso.

Leha ho le joalo ho na le ha ho pelaelo hore hore transduction o etsoang ho tsoa ka lebaka la bokhoni ba acid e phosphatidic, amang sebōpeho lisele tsa lera ea, lera la laola mosebetsi oa enzyme, 'me hape le seabo sa sebelisana le lisele limolek'hule lera protheine.

Kopo ea acid e phosphatidic

Lithuto na antioxidant mosebetsi oa derivatives ea acid e phosphatidic, a khanna ka ho ithuta dithulaganyo ea mohlala le amang beha dintho tsa likokoana-hloko li bontšitse hore seo ho thoeng ke phosphatidic acid e mimetics rua antioxidant plurality ya mekgwa ya bohato.

lesedi akaretsang ka tataiso ea ketso ea acid e phosphatidic lumella ho sebelisa le metabolites ea eona e leng tlhahiso ea dintho biologically mafolofolo nakong reretsoeng ho ntlafatsa tshebetso le mamello ea liseleng.

Ho nka bohato ka boemo ba ka lisele, metsoako joalo u se ke ua susumelletsa, empa feela normalize lisele; ntlha ea bohlokoa ke ho fokotsa kotsi ea ho ba le liphello tse sa khothatseng lehlakoreng.