Antiplatelet moemeli "Clopidogrel": litaelo tsa tšebeliso

Le bolela "clopidogrel" taeo pukwanana hlalosang e le moemeli antiplatelet, e thehiloeng bolokwa fokotseha platelet aggregation hlohlelletsoa ke agonists tse sa tšoaneng. Ho feta moo, lithethefatsi ena e na le tshwaileng e le phello vasodilatig. Nako e telele ho sebelisoa ha "clopidogrel" ho lokisetsa (litaelo bakeng sa ho sebelisoa e bua haholo ka hloko hore e khethehileng) ha a lumelle lisele tsa mali e qala ya ho theha clots mali, bopa lihlopha tsa aggregates. Kahoo, ke sesebelisoa sa ho fokotsa kotsi ya lichapo le lefu la pelo etsahala maemong a moo thrombus, e leng e thehiloe e le karolo e moqotetsane tsa mothapo, 'me ho thibela mali ho phalla overlaps le phallo ea limatlafatsi le oksijene ho lisele tse likokoana-hloko.

Fumaneha kajeno moriana "Clopidogrel" feela ka mokgwa wa ho potoloha matlapa pinki. Sebopeho sa e mong le e pellet ka motsoako ka sehloohong e kenyeletsa milligrams mashome a supileng a metso e mehlano tsa clopidogrel. Malandi ke dintho tse kang oli Castor, starch pregelatinized, macrogol, lactose anhydrous, magnesium stearate le microcrystalline selulose. Sebopeho sa khetla kenyelletsa ditokiseletso nhua polyethylene glycol 400 le 6000, hypromellose, thaethaniamo dioxide, le aluminium letšeng.

Nka le pilisi "Clopidogrel" litaelo bakeng sa ho sebelisoa ke Lekgotla e le hore ho thibela setorouku, myocardial infarction, thrombosis tsa methapo pheriferale tse kang, ka tšohanyetso la pelo lefu le liketsahalo tse ling tse ischemic ka bakuli ba atherosclerosis. Ho phaella moo, lithethefatsi ena e atisa ho laetsoeng hammoho le asiti acetylsalicylic bakeng sa thibelo ea seo ho thoeng ke "mathata thrombotic" ka ketsahalo ea ho lefu hlobaetsang gogoga.

Sebelisa e bolela "Clopidogrel" litaelo bakeng sa ho sebelisoa e tieo sa kgothaletswa bakeng sa batho ba nang le alejiki itsoara joang ho clopidogrel kapa mamellane motho ea likarolo efe kapa efe ea thusang tse sebopeho lona. Kapa lokela ho nka matlapa ana ho bakuli ba a hlobaetsang le tsoa mali (mohlala, liso tsa ka maleng peptic) kapa tse matla ho hloleha sebete. Lenane la contraindications ka tieo, ntle le tse ka holimo ho tsohle, e kenyeletsa ea bokhachane, ea lilemo li ka tlase ho lilemo tse leshome le metso e robeli la lilemo le nako ea ho diabolololo. Tabeng ea khaello lactase kapa mamellane lactose ka tsela e tšoanang ha ba nke matlapa "clopidogrel". Ka cardiologists haholo tlhokomelo ho laela lithethefatsi ena ho bakuli ba nang le phumano ea "ho hloleha liphio" kapa "mofuta o bonolo oa ho hloleha sebete." Ha batho ba mefuta eohle maemo pathological hore haholo eketsa menyetla ea ho tsoa mali, 'me tšekamelo ea ho bona' me u se ke ua sebelisa lithethefatsi "clopidogrel". Qetellong, ho e sa kgothaletswa ho nka pheko ena hammoho le meriana "Warfarin" "Heparin", le batho bao e seng steroidal-ba khahlanong le a hlabang lithethefatsi.