Lithethefatsi "Doxycycline", analogues le litla bona.

"Doxycycline" e bolela e loantsang likokoana bakeng sa tšebeliso systemic. Hammoho le ke "Doxycycline" analogues ya lithethefatsi e ne e akarelletsa ho tetracyclines sehlopha. Ba na le mefuta e fapaneng ka ho lekaneng bohato lohle ikemiseditse ho loantšeng likokoana-hloko.

The tummeng ka ho fetisisa ka ho lokisetsa "Doxycycline" counterparts - ka "JUnidoks soljutab", "Doxycycline gidlohlorid", "Doksibene", "Doxycycline-Darnitsa" 'me ba bang ba bang. hangata ha ho, u ka bona tsela eo batho ba belaela hore na o lokela ho reka, "Doxycycline" kapa "JUnidoks", ka mohlala. Re lokela ho hlokomela hore pharmacodynamics ka formulations tsena ke se tšoanang. Kahoo, ba ile ba ba mafolofolo khahlanong le a mob mobile ea HIV (Stamphylococcus spp., Streptococcus spp. , Actinomyces Iseraele, Clostridium spp., Listeria monocytogens, Bacillus anthracis) le a mob mobile (of Neisseria gonorrhoeae, ea Vibrio cholerae, ea Bordetella mokhokhothoane, ea Yersinia spp., Of Enterobacter spp., Klebsiella spp., Escherichia coli, Salmonella spp., Shigella spp.) mikroargonizmov. Ela hloko "doxycycline" le analogues lona Mycoplasma spp., Rickettsia spp., Treponema spp., Borrelia burgdorferi, Chlamydia spp., Tse ling tsa tse bonolo (ho akarelletsa le Entamoeba histolytica, Plasmodium falciparum). nahanela ho fetisisa ho analogs "Doxycycline» ba haemophilus ntaramane (91-96%) le likokoana-hloko intracellular.

Feela boima ntlha eo e fapana ho tloha lithethefatsi, "Doxycycline" counterparts - ke hore ke e nyenyane ho feta mekhoa e meng ea tetracycline mpefatsa le limela mala, hammoho le ka nako ea nkang khato e eketsehileng 'me ka ho feletseng ho feta absorption. Lithibela-mafu ho tloha letoto la lihlooho tse tetracycline phunyeletse lisele le thibela metsoako kgolo ya likokoana-hloko, teng ho na le. Ho ea ka tekanyo e oa mosebetsi ea baktheria ho lokisetsa "Doxycycline hydrochloride" o phahametse tetracyclines tse ling tsohle, ho akarelletsa le tsa tlhaho.

E le lithethefatsi "Doxycycline", analogues lona ba na le matšoao a kang a latelang:

- infektsyai otolaryngology;

- pampitšana tšoaetso ea matšoafo;

- tsoaetsanang ea genitourinary tsamaiso e khopo;

- dinama tse nyenyane tse le tšoaetso ea bonolo, 'me letlalo;

- e le tšoaetso ea ea pampitšana biliary le pampitšana gastrointestinal;

- osteomyelitis, brucellosis, whooping khohlela;

-sifilis, yersiniosis, malaria, yaws, Q feberu, legionellosis, feberu ea mala, typhus, lefu Lyme, chlamydia fapaneng diriswa, bacillary le amoebic letšollo, k'holera, tularemia, actinomycosis;

- e le karolo ea kalafo palo yohle - granulocytic ehrlichiosis, leptospirosis, psittacosis, trachoma, psittacosis;

- subacute baktheria endocarditis, septicemia, peritonitis.

Ho hanela ho sebelisoa ha "Doxycycline" ka nahanela matla ho tetracyclines, haholo sebete ho hloleha, porphyria, bokhachane, diabolololo (bakeng sa nako ya ea lithethefatsi ho tloha anyesa lokela hana), bana ba lilemo li ho fihlela ho lilemo tse 12. Mehato lokela ho nka lithethefatsi bakeng sa batho ba ileng ba tlameha e sa tloaelehang sebete mosebetsi, leukopenia.

Lithethefatsi "Doxycycline" e ka ba le liphello tse bohloko ka:

- tsamaiso ea methapo (ketso ea mofuta chefo ea tsamaiso ea methapo e bohareng, intracranial khatello e ka holimo ho tloaelehile);

- makala a utloeng (lerata bonahala litsebeng le);

- tshilong ya dijo tsamaiso e khopo (enterocolitis, ho hlatsa, ho nyekoa ke pelo, letšollo kapa pipitlelano, gastritis, dysphagia, glossitis, esophagitis, e le pontšo ea mala le duodenum 12);

- tsamaisong pelo le methapo (edema, tachycardia);

- makala a hematopoiesis (thrombocytopenia, eosinophilia, haemolytic khaello ea mali, neutropenia, porphyria);

- itšoara joang, e leng se bontšang e allergy (letlalo redness, ho hlohlona, anaphylactoid itšoara joang, maculopapular lekhopho, Stevens-Johnson lefu, antigionevrotichesky edema);

- tse ling tse (lefu la sebete, nyooko, myalgia, arthralgia, photosensitivity, haholo discoloration ya leino enamel, ho ruruha ka anogenital sebakeng, candidiasis, goiter).

Ka overdose ea "Doxycycline" o ka 'na a hlokomela matšoao a latelang: hepatotoxicity, liphello ho feta phatlalletsoang lehlakoreng. Tabeng ena, u lokela ho hang-hang ba retelehela ho tlhokomelo ea bophelo, ho phumulwa ea lithethefatsi le boitšoaro kalafo bontshang matshwao (kaha ha ho na pheko ea itseng), o lokela ho boela ho boloka le ho hlokomela, ka moo ho tsoela pele mesebetsi ea bohlokoa.