Bacteriophages: mefuta e le morero oa

Phage lysis - tshebetso la timetso ea libaktheria ke phages, hangata le hlaha ka lekala ameha nakong hlaphoheloa ho itlelang feela. Haeba ho intša ba le pholiso e-s'o be teng, 'mele o ka thusoa ke e hlahisang bacteriophage ngollana, ho fellang ka khampani ya meriana. Bitsoa bacteriophages livaerase libaktheria tse phunyeletse le ho etsa hore shoa hoa bona (lysis) sebokeng le eena habonolo liseleng tse sa bonahaleng tse.

Ka bacteriophage Segerike le bolela "jang ea libaktheria." Ka tlhaho, tse phelang tsena ke tse fapa-fapaneng haholo le tse khōlō ka ho fetisisa ea tsejoang kateng hona joale lihlopha bongata ba kokwanahloko. Phages ke likokoana-hloko tse fapaneng ho tloha limela, liphoofolo le sebopeho ba motho, ho feta li rarahane. Li fumanoa ka pula, moea, mobu, lijo, ka letlalo bafo, boea ba liphoofolo, ka mantsoe a mang, kae kapa kae moo ho na le libaktheria.

Lilemong tsa morao tjena, thahasella ho hōla bacteriophages li sebelisoa e le mefuta e meng ea ho lithibela-mafu. Sena ha se makatse, 'me ba le lithethefatsi tse ling ho toba ama likokoana-hloko. Leha ho le joalo, lithibela-mafu li tsejoa e le hantle e kotsi ha se feela ho limela pathogenic, empa le bakeng sa utility e. Bacteriophages, mefuta ea tse fapaneng, ho sebetsa khetha, feela bakeng sa "bona" libaktheria, siea maloanlahla ho eena. Ha e le hantle, kahoo bo-rasaense le ba ne ba sa qapa mabitso bona, ho ba bonolo haholo ho ba bitsa ka ho latellana libaktheria tseo ba li pepesa.

Bacteriophages: Types

Hlahisa streptococcal, coliform Proteaceae, klebsiellezny, Staphylococcus, Pseudomonas, Salmonella, letšollo, feberu ea mala bacteriophage hammoho le "Intestifag" le "Piobakteriofag".

litokisetso Active e laolwang ke lengolo la bona la ho hlapholla moo ba lysis nahanela setso. Kahoo, titer la 10 tekanyo e ea bobeli e bolela hore lipontsuoa lytic bacteriophage thepa a sebetsang a ka ho hlapholla ya 1 000 000 ka makhetlo a. Ka mocheso oa 4-6 C lithethefatsi ba boloke thepa tsa bona ho fihlela ho lilemo tse 12.

Ho itšetlehile ka liforomo ho lokolloa fapana ka bacteriophages mosebetsi. Types of lithethefatsi ka ama likokoana-hloko bobeli motho, 'me ka' maloa hang-hang. Monophages ama mefuta e 'maloa ea libaktheria le' ngoe. K rarahaneng litokisetso (polyvalent) kenyeletsa bacteriophage "Sekstafag" e leng kgona ho ka nako thibela metsoako mosebetsi oa staphylococci, streptococci, ho akarelletsa le enterococci, Pseudomonas le Escherichia coli, Proteus, Klebsiella. Ho feta moo, ho na le "Intestifag" ne a rerile hore ho phekola tšoaetso ea mala, e kenyelletsa ditokiseletso e Salmonella, feberu ea mala, letšollo, Proteus, coli le streptococcal (hatella enterococci) phages.

Lithethefatsi sebelisoa ka dysbacteriosis, tšoaetso mala, inflammations ea tsamaiso urogenital le sethusathuto broncho-methapo ho phekola dithulaganyo maswe, hammoho le mafu a ea cavity molomo le sinuses. Di sebelisoa e le ka hare, ho akarelletsa le ka sebōpeho sa enemas, 'me sebakeng sa heno - ho rinse, hlatsoa maqeba, douching. Mohlala, "The Bacteriophage Klebsiella polyvalent hloekisa" bakeng sa kalafo ozeny, rinoskleromy, tšoaetso e bakiloeng ke baktheria Klebsiella serame sa matšoafo, o ile a sebelisa ka ho inhalation ka diso trachea, larynx le pharynx, laolwa turunda soaked ka mokelikeli, nattokinase, sebediswa bakeng sa washings ka sinusitis. Ha cystitis, enterocolitis, urethritis, serame sa matšoafo lithethefatsi e nkiloeng ka molomo.

Bacteriophages ba le boima ba menyetla fetang lithibela-mafu. Ba na le litla na lehlakoreng, ba abetsoe esita le masea le basali ba baimana, ba ha ba lemalla. Ba ka ho kopantswe le lithethefatsi leha e le efe, hammoho le ho sebelisa bakeng sa thibelo ea mafu a tšoaetsanoang. litokisetso tsena ba le tšusumetso e molemo ka ntshetsopele ya maloetseng, u se ke ua hatella ea limela tsa tlhaho le phello ea bona e totobala haholo ka hare ho lihora tse 2-4 ka mor'a a e-ja. Ha ba be le ho hanyetsa likokoana-hloko.

drawback mong ke bacteriophages. Types of sebelisoa kajeno ka moriana, leha ho le joalo tse 'maloa, e leng se lekanyetsang ho sebelisa ha bona ho tšoaetsoa mafu tse ngata.

kopo Outlook

E le hore ba ka katleho sebetsa lihlahisoa tsa likokoana-hloko, e ke ho hlokahala hore ho fumana hore na nahanela ea libaktheria ho bona. Leha ho le joalo, bo-rasaense ba hlokometse e paterone tse thahasellisang: ho nahanela ba microorganisms ho phages ha fokotswa, empa ho ena le hoo eketsa, ka lebaka la ho ya matlafatso ea lihlahisoa le litso tse ncha. Ho fihlela joale, ho staphylococcal bacteriophage katleho lyse 90% ea mefuta eohle ea libaktheria sa lokolla nakong diso maswe.

A mangata a tšoaetsanoang lefu ditsebi lumela hore phage phekolo e tla haufinyane revolutionize ntoa e khahlanong le mafu. Immunologists bona le tšepo ea ho sebelisa chelete tsena moo Immunopreparat na matla. Ho ea ka lithuto tsa katisediwa ka lilemo tse seng kae tse latelang, e mong oa libakeng ho fetisisa tsepisa tsa pharmacology tla tlhahiso ea phages.